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  • Tom Ellis Lab

Antibiotics Biosynthesis

Updated: Apr 9, 2019

Ali Awan’s paper on engineering Baker’s yeast to produce and secrete active antibiotics is online in Nature Communications with lots of news coverage too.


This project is our pilot study to bring biosynthesis of a fungal antibiotic into yeast. Fungi naturally produce many antibiotics to keep bacteria at bay, and in the age of antimicrobial resistance (AMR) we want to use yeast synthetic biology to help out the eukaryotes in this evolutionary arms race.


· Research highlights: Yeast cells turned into penicillin factories: Nature

· Could good old yeast spell the end of superbugs?: The Daily Mail

· Cheers! Beer holds the key to new antiobiotics: The Times (paywall)

· Baker’s yeast makes Pencillin: The Hippocratic Post

· Mass production in yeast: SGD Yeast Genome News

· Engineering baker’s yeast to produce penicillin molecules: Imperial College London

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CONTACT US

Tom Ellis - Professor of Synthetic Genome Engineering

Imperial College Centre for Synthetic Biology (IC-CSynB) and the Department of Bioengineering at Imperial College, London

Phone: +44-20-7594-7615

Email: t.ellis@imperial.ac.uk

Lab Address

609 Bessemer Building, Imperial College, London
South Kensington Campus, London SW7 2AZ, United Kingdom

 

Office Address

704 Bessemer Building, Imperial College, London
South Kensington Campus, London SW7 2AZ, United Kingdom